Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the NFC and AFC favorites Detroit Lions (11-1) and Kansas City Chiefs (11-1) were both pushed in the second half and held on in the closing seconds for victories. The full NFL schedule continues on Sunday and Monday with more big watch and wager action. That includes the most anticipated late afternoon interconference clash between the Philadelphia Eagles and Baltimore Ravens. The two Sunday night and Monday night prime time games will conclude the action with more picks and props driving engagement and interest for the San Francisco 49ers at Buffalo Bills and MNF Cleveland Browns at Denver Broncos.

NFL Week 13 Odds

Pro football oddsfrom FanDuel Sportsbook and top online sportsbooks refresh periodically and are subject to change, including on props and live betting. Bet types, odds and betting terms with listed point spreads on favorites.

  • San Francisco 49ers at Buffalo Bills (-6.5), Over/Under 44.5 points

Sunday Night Football on NBC at 8:20 p.m. ET

  • Cleveland Browns at Denver Broncos (-5.5), O/U 42.5

Monday Night Football on ABC and ESPN at 8:15 p.m. ET

Sports betting in New York and Colorado is fueling interest in the Bills and Broncos with prime time games driving additional engagement and watch and wager action. NFL weather is cold in Buffalo near 20 degrees and likely show showers.

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49ers-Bills Matchups And Props

Bob Stoll of Dr. Bob Sports provides additional matchups and advance stats for the 49ers-Bills (check back) and Browns-Broncos matchups with information you can bet on. The updated injury reports are always worth monitoring as more key injuries and quarterback changes impact matchups and results.

  • 49ers QB Brock Purdy passing yards: Over/Under 226.5 – Bet under
  • BUF QB Josh Allen passing yards: O/U 219.5, rushing 36.5
  • 49ers RB Christian McCaffrey rushing yards: O/U 63.5, receiving 30.5
  • BUF RB James Cook rushing yards: O/U 63.5, receiving 16.5
  • 49ers WR Jauan Jennings receiving yards: O/U 55.5
  • 49ers WR Deebo Samuel receiving yards: O/U 42.5
  • 49ers TE George Kittle receiving yards: O/U 48.5
  • BUF WR Khalil Shakir receiving yards: O/U 55.5
  • BAL TE Isaiah Likely receiving yards: O/U 26.5
  • LAC WR Ladd McConkey receiving yards: O/U 64.5

Browns-Broncos Matchups And Props

  • Jameis Winston has a 10.6-yard average depth of target since taking over as Cleveland’s starter compared to Deshaun Watson averaging just 7.1 air yards per attempt.
  • Part of the added downfield aggressiveness is due to Winston and part is due to the Browns offensive line improving after four of the five starters missed games in the first half of the season. Winston has a 51% clean pocket rate (2nd).
  • Broncos’ interior defender Zach Allen ranks 5th in pass-rushing efficiency but he was wearing a walking boot on his right foot and is nursing a heel injury.
  • Cleveland backup LT Germain Ifedi could struggle across from edge defender Nik Bonitto, who ranks 14th in pass-rushing efficiency.
  • Denver interior defender John Franklin-Myers has 31 pressures (15th) and he will be contained by RG Wyatt Teller, who ranks 14th in pass-blocking efficiency.
  • Browns WR Jerry Jeudy leads the NFL with 22 receptions on balls thrown between 10 and 19 yards in the air. Cleveland’s coaching staff will look to get Jeudy in the slot rather than on the outside across from CB Pat Surtain, who is allowing a league-low 0.47 yards per cover snap. Broncos nickelback Ja’Quan McMillian is surrendering 1.48 yards per cover snap in the slot (3rd-worst).
  • Cleveland edge defender Myles Garrett had 3.0 sacks last week against Pittsburgh, but he will be limited on Monday night by LT Garett Bolles, who ranks 6th in pass blocking efficiency.
  • Denver’s offense has a yards per pass play versus single-high safety coverage a league-high 26% more than versus two-high and Bo Nix has a favorable matchup as the Browns defense leads the NFL with a 63% single-high safety rate.
  • The Broncos’ playoff chances would increase to 78% with a win by our metrics but would drop to roughly a coin flip if Denver were to lose.
  • Our model favors the Broncos by 7.3 points, with a predicted total of 45.6 points, and the game total over is a strong opinion.
  • CLE QB Jameis Winston passing yards: Over/Under 230.5, rushing 43.5
  • DEN QB Bo Nix passing yards: O/U 220.5, rushing 18.5
  • CLE RB Nick Chubb rushing yards: O/U 56.5
  • DEN RB Javonte Williams rushing yards: O/U 38.5, receiving 14.5
  • CLE WR Jerry Jeudy receiving yards: O/U 58.5
  • CLE TE David Njoku receiving yards: O/U 47.5
  • DEN WR Courtland Suttons receiving yards: O/U 63.5
  • DEN WR Devaughn Vele receiving yards: O/U 34.5

Player Props: Broncos QB Bo Nix over 18.5 rushing yards. The Browns play the 4th most man coverage in NFL, and have allowed 64 QB runs, also 4th most in NFL.

The player prop picks posted on these NFL betting preview pages at Forbes have been scoring and cashing in Week 4, Week 5, Week 6, Week 7, Week 8, Week 9, Week 10, Week 12 and Week 13.

Eagles-Ravens

  • Philadelphia will likely be without key players on both sides of the ball this week. WR DeVonta Smith is averaging 0.47 EPA/target (18th) but he will be sidelined dealing with a hamstring injury.
  • Eagles CB Darius Slay is conceding 0.80 yards per cover snap (13th) but he was ruled out after suffering a concussion last week. Lamar Jackson will attack Philadelphia backup cornerback Isaiah Rodgers with WR Rashod Bateman, who is averaging 0.63 EPA/target (5th).
  • Our model favors the Ravens by 6.3 points, with a predicted total of 52.8 points, and the Eagles apply to a 37-90-3 ATS situation that is based on their 3 consecutive wins and spread wins. It also doesn’t hurt that Lamar Jackson is now 31-5-2 ATS in regular season games when not favored by 4 points or more.

More sports betting news, stats, player props and information you can bet on as the NFL draws more watch and wager action with player props driving additional engagement, entertainment and interest.

You can bet on it.

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